A recent study by researchers at Yale School of Medicine, New York University Langone Health and Washington University School of Medicine, claims that the ketogenic diet (high fat, low carbohydrate diet) is capable of mitigating clinical outcomes of coronavirus disease 2019 (COVID-19) in elderly people by improving immune-metabolic functions and reducing inflammation. The study is currently available on the bioRxiv* preprint server.
Since the emergence of the COVID-19 pandemic, several studies have identified age as the strongest risk factor associated with a high mortality rate in patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. In the United States, about 80% of COVID-19 related deaths occurred in people who were more than 65 years old.
In general, the activity of the immune system is compromised in older adults because of age-related impairment in B cell and T cell activation together with inflammasome-induced low-grade systemic inflammation. However, studies investigating COVID-19